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  • Cystatin C Antibodies

Invitrogen

Cystatin C Polyclonal Antibody

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Cite Cystatin C Polyclonal Antibody

  • Antibody Testing Data (1)
Cystatin C Antibody in Western Blot (WB)
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Cystatin C Antibody in Western Blot (WB)
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Cystatin C Antibody (PA5-145481) in WB

Western blot analysis of Cystatin C in various lysates. Samples were incubated with Cystatin C polyclonal antibody (Product # PA5-145481) using a dilution of 0.2 µg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG secondary antibody at a dilution of 0.2 µg/mL. Lane 1: Gallus Serum; Lane 2: Gallus Cerebrum lysate; Lane 3: Gallus Testis lysate; Lane 4: Human Milk. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Cystatin C Antibody in Western Blot (WB)
Cystatin C Polyclonal Antibody

Product Details

PA5-145481

Applications
Tested Dilution
Publications

Western Blot (WB)

0.01-2 µg/mL
-
Product Specifications

Species Reactivity

Chicken, Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Chicken Cys-C protein, Ser24-Gln139 (Accession #P01038)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% Proclin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3093569

Target Information

Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AD8; bA218C14.4 (cystatin C); Cystatin; cystatin 3; Cystatin-3; Cystatin-C; Cystatin3; CystatinC; Egg-white cystatin; epididymis secretory protein Li 2; Gamma-trace; MGC117328; Neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; Ovocystatin; Post-gamma-globulin; RP23-250M11.9

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Gene Aliases: ARMD11; CST3; HEL-S-2

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UniProt ID: (Human) P01034, (Chicken) P01038

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Entrez Gene ID: (Human) 1471, (Chicken) 396497

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Function(s)
beta-amyloid binding protease binding endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity protein binding identical protein binding
Process(es)
defense response negative regulation of peptidase activity negative regulation of collagen catabolic process negative regulation of extracellular matrix disassembly negative regulation of endopeptidase activity regulation of tissue remodeling extracellular fibril organization cellular protein metabolic process negative regulation of proteolysis negative regulation of elastin catabolic process negative regulation of blood vessel remodeling
It has to be done as per old AB suggested Products section.
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