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Invitrogen
Cyclin F Polyclonal Antibody
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FIGURE: 1 / 8
Cyclin F Antibody (PA5-67186) in IHC
Product Details
PA5-67186
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Concentration
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Storage buffer
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RRID
Product Specific Information
Immunogen sequence: GDQESEGEKEG DVTAPSGILD VTVVYLNPEQ HCCQESSDEE ACPEDKGPQD PQALALDTQI PATPGPKPLV R
Highest antigen sequence identity to the following orthologs - mouse 69%, rat 69%.
Target Information
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CDK2; Cyclin-F; EC 2.7.11.22; F-box only protein 1; G2/mitotic-specific cyclin-F; P33(CDK2)
Gene Aliases: CCNF; FBX1; FBXO1
UniProt ID: (Human) P41002
Entrez Gene ID: (Human) 899
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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