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  • Complement Factor B Antibodies

Invitrogen

Complement Factor B Polyclonal Antibody

View all (20) Complement Factor B antibodies

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Cite Complement Factor B Polyclonal Antibody

  • Antibody Testing Data (1)
Complement Factor B Antibody in Western Blot (WB)
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Complement Factor B Antibody in Western Blot (WB)
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Complement Factor B Antibody (PA5-89110) in WB

Western blot analysis of Complement Factor B in extracts of rat serum. Samples were incubated with Complement Factor B Polyclonal antibody (Product # PA5-89110) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Complement Factor B Antibody in Western Blot (WB)
Complement Factor B Polyclonal Antibody

Product Details

PA5-89110

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 80-420 of human Complement factor B (CFB) (NP_0017012)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.24 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2805362

Product Specific Information

Immunogen sequence: GSWSTLKTQD QKTVRKAECR AIHCPRPHDF ENGEYWPRSP YYNVSDEISF HCYDGYTLRG SANRTCQVNG RWSGQTAICD NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG SWSGTEPSCQ DSFMYDTPQE VAEAFLSSLT ETIEGVDAED GHGPGEQQKR KIVLDPSGSM NIYLVLDGSD SIGASNFTGA KKCLVNLIEK VASYGVKPRY GLVTYATYPK IWVKVSEADS SNADWVTKQL NEINYEDHKL KSGTNTKKAL QAVYSMMSWP DDVPPEGWNR TRHVIILMTD GLHNMGGDPI TVIDEIRDLL YIGKDRKNPR E; Positive Samples: Rat serum

Target Information

Factor B is a component of the alternative complement pathway. The protein is a single chain polypeptide with a molecular mass of 93 kDa. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Bb together with C3b forms the alternative pathway C3 convertase C3bBb.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: alternative-complement pathway C3/C5 convertase; B-factor, properdin; C3/C5 convertase; complement component 2 (within H-2S); complement factor B; DADB-122G4.5; Factor B; histocompatibility 2, complement component factor B; properdin; properdin factor B

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Gene Aliases: AI195813; AI255840; B; Bf; C2; Da1-24; Fb; H2-Bf

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Entrez Gene ID: (Mouse) 14962, (Rat) 294257

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Function(s)
serine-type endopeptidase activity peptidase activity serine-type peptidase activity hydrolase activity
Process(es)
immune system process proteolysis complement activation complement activation, alternative pathway cell proliferation innate immune response response to thyroid hormone response to lipopolysaccharide
It has to be done as per old AB suggested Products section.
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