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  • Primary Antibodies ›
  • Complement C5b/C9 Antibodies

Invitrogen

Complement C5b/C9 Monoclonal Antibody (3R2/0)

View all (2) Complement C5b/C9 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Complement C5b/C9 Monoclonal Antibody (3R2/0)

Product Details

MA5-28502

Applications
Tested Dilution
Publications

Western Blot (WB)

Assay-dependent
-

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent
-

Flow Cytometry (Flow)

Assay-dependent
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

3R2/0

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.18 mg/mL

Purification

Protein A

Storage buffer

BBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2745462

Product Specific Information

This antibody recognizes the SC5b-9 complex of around 330 kDa. Both the classical and alternative complement pathways result in the formation of the cytolysis inducing C5b-9 complex.

Target Information

An association study of C5 haplotypes and genotypes in individuals with chronic hepatitis C virus infection shows that individuals homozygous for the C5_1 haplotype have a significantly higher stage of liver fibrosis than individuals carrying at least 1 other allele.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C5a anaphylatoxin; c5b-9; C5b9; Complement C5; Complement component C9; prepro-C5

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Gene Aliases: ARMD15; C5; C5a; C5b; C5D; C9; C9D; CPAMD4; ECLZB

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UniProt ID: (Human) P01031, (Human) P02748

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Entrez Gene ID: (Human) 727, (Human) 735

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Function(s)
endopeptidase inhibitor activity receptor binding protein binding chemokine activity
Process(es)
activation of MAPK activity in utero embryonic development chemotaxis response to stress inflammatory response complement activation complement activation, alternative pathway complement activation, classical pathway cell surface receptor signaling pathway G-protein coupled receptor signaling pathway positive regulation of vascular endothelial growth factor production negative regulation of macrophage chemotaxis negative regulation of endopeptidase activity cytolysis regulation of complement activation positive regulation of angiogenesis cell chemotaxis positive regulation of chemokine secretion mitophagy in response to mitochondrial depolarization
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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