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Invitrogen
Complement C4d Monoclonal Antibody (10-11)
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Product Details
MA1-83082
Species Reactivity
Published species
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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RRID
Product Specific Information
This antibody does not react with bovine, cat, dog, guinea pig, mouse, rabbit, rat or sheep.
It has been reported that this antibody works very well on acetone-fixed, frozen renal biopsies. Strong staining is observed in the glomeruli and in some cases the peritubular capillaries. Clone 10-11 has given variable results on formalin-fixed, paraffin-embedded sections. It has been observed that pre-treatment with 88% formic acid for 20 minutes at room temperature is beneficial.
Mouse anti Human C4d antibody, clone 10-11 recognizes the secreted protein complement component 4d (C4d).
Target Information
C4 is a component of the classical complement pathway and is split by activated C1s to C4a and C4b. Together C2a and C4b forms the classical C3 convertase. The molecular mass of C4 is 204 kDa and it consists of 3 subunits: a (97 kDa), b (75 kDa) and g (33 kDa).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acidic C4; Acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; c4 complement; C4A anaphylatoxin; C4D; Chido form of C4; Complement C4-A; Complement C4-B; complement C4B1a; DADB-112B14.11; FLJ60561; MGC164979; MHC class III region complement; Rodgers form of C4
Gene Aliases: C4; C4A; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B1; C4B12; C4B2; C4B3; C4B5; C4B_2; C4BD; C4F; C4S; CH; CO4; CPAMD2; CPAMD3; RG
UniProt ID: (Human) P0C0L4, (Human) P0C0L5
Entrez Gene ID: (Human) 720, (Human) 721, (Human) 100293534
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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