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Invitrogen
Chemerin Monoclonal Antibody (372402)
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FIGURE: 1 / 1
Chemerin Antibody (MA5-24115) in Neu
Product Details
MA5-24115
Species Reactivity
Host/Isotype
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Immunogen
Conjugate
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Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Chemerin; Retinoic acid receptor responder protein 2; TIG-2; TIG2HP10433
Gene Aliases: 0610007L05Rik; AI303516; Rarres2
UniProt ID: (Mouse) Q9DD06
Entrez Gene ID: (Mouse) 71660
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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