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Invitrogen
Cathepsin K Polyclonal Antibody
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FIGURE: 1 / 3
Cathepsin K Antibody (PA5-14270) in IHC (P)
Product Details
PA5-14270
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
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Purification
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RRID
Product Specific Information
This antibody is predicted to react with bovine, porcine, non-human primate and rabbit based on sequence homology.
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cat K; Cathepsin K; Cathepsin O; cathepsin O1; Cathepsin O2; Cathepsin X; MGC23107; minisatellite 10q detected by probe MMS10
Gene Aliases: AI323530; catK; CTS02; CTSK; CTSO; CTSO1; CTSO2; MMS10-Q; Ms10q; PKND; PYCD
UniProt ID: (Human) P43235, (Mouse) P55097
Entrez Gene ID: (Human) 1513, (Mouse) 13038
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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