Bioss

Cathepsin H/CTSH Polyclonal Antibody

View all (14) Cathepsin H antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers
Cathepsin H/CTSH Polyclonal Antibody

Product Details

BS-1670R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Capsin H, amino acids 71-170.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: aleurain; Cat H; CATH; Cathepsin B3; Cathepsin BA; N-benzoylarginine-beta-naphthylamide hydrolase; Pro-cathepsin H

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Gene Aliases: ACC-4; ACC-5; ACC4; ACC5; AL022844; CPSB; CTSH

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UniProt ID: (Human) P09668, (Rat) P00786, (Mouse) P49935

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Entrez Gene ID: (Human) 1512, (Rat) 25425, (Mouse) 13036

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Function(s)
endopeptidase activity aminopeptidase activity cysteine-type endopeptidase activity serine-type endopeptidase activity protein binding peptidase activity cysteine-type peptidase activity cysteine-type endopeptidase activator activity involved in apoptotic process HLA-A specific activating MHC class I receptor activity thyroid hormone binding peptidase activator activity involved in apoptotic process kininogen binding protein complex binding protein self-association hydrolase activity
Process(es)
metanephros development T cell mediated cytotoxicity adaptive immune response immune response-regulating signaling pathway proteolysis apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of cell proliferation positive regulation of gene expression positive regulation of epithelial cell migration neuropeptide catabolic process bradykinin catabolic process positive regulation of peptidase activity antigen processing and presentation positive regulation of cell migration zymogen activation protein destabilization response to retinoic acid membrane protein proteolysis negative regulation of apoptotic process surfactant homeostasis cellular protein metabolic process positive regulation of angiogenesis proteolysis involved in cellular protein catabolic process dichotomous subdivision of terminal units involved in lung branching ERK1 and ERK2 cascade cellular response to thyroid hormone stimulus positive regulation of apoptotic signaling pathway spermatogenesis
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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