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  • Cathepsin B Antibodies

Invitrogen

Cathepsin B Monoclonal Antibody (J11-A11)

View all (24) Cathepsin B antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Cathepsin B Monoclonal Antibody (J11-A11)

  • Antibody Testing Data (2)
Cathepsin B Antibody in Immunocytochemistry (ICC/IF)
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Cathepsin B Antibody in Immunocytochemistry (ICC/IF)
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Cathepsin B Antibody (MA5-42576) in ICC/IF

Immunocytochemistry-Immunofluorescence analysis of Cathepsin B in HepG2 cells (red) using Cathepsin B Monoclonal Antibody (Product # MA5-42576). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Cathepsin B Antibody in Immunocytochemistry (ICC/IF)
Cathepsin B Antibody in Western Blot (WB)
Cathepsin B Monoclonal Antibody (J11-A11)

Product Details

MA5-42576

Applications
Tested Dilution
Publications

Western Blot (WB)

1:5,000-1:10,000
-

Immunocytochemistry (ICC/IF)

1:50
-
Product Specifications

Species Reactivity

Human, Zebrafish

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

J11-A11

Immunogen

Synthetic peptide within human cathepsin b aa 300-338
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 40% glycerol, 0.2% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911717

Product Specific Information

Positive Control: SW480, HepG2

Subcellular Location: Lysosome, secreted

Target Information

Cathepsin B is a lysosomal cysteine protease that has been implicated in the pathogenesis of rheumatoid arthritis, muscular dystrophy and tumor metastasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: amyloid precursor protein secretase; APP secretase; APPS; capthepsin B, b; Cathepsin B; cathepsin B, a; Cathepsin B1; cysteine protease

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Gene Aliases: APPS; CPSB; CTSB; id:ibd1201; wu:fa13g05; wu:fb34e12; zgc:55862; zgc:65809; zgc:77181

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UniProt ID: (Human) P07858

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Entrez Gene ID: (Human) 1508, (Zebrafish) 406645, (Zebrafish) 569298

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Function(s)
cysteine-type endopeptidase activity serine-type endopeptidase activity protein binding collagen binding peptidase activity cysteine-type peptidase activity kininogen binding peptide binding proteoglycan binding protein self-association hydrolase activity
Process(es)
toll-like receptor signaling pathway proteolysis autophagy spermatogenesis skeletal muscle tissue development response to wounding response to glucose response to organic cyclic compound response to amine collagen catabolic process epithelial cell differentiation regulation of apoptotic process response to peptide hormone response to ethanol decidualization viral entry into host cell regulation of catalytic activity proteolysis involved in cellular protein catabolic process negative regulation of cell death response to interleukin-4 cellular response to mechanical stimulus cellular response to thyroid hormone stimulus dorsal/ventral pattern formation fin regeneration convergent extension epiboly
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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