Invitrogen

Cathepsin B Polyclonal Antibody

Name: Cathepsin B Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-17006

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View all (24) Cathepsin B antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (4)
Advanced Verification (1)

Cathepsin B Antibody in Western Blot (WB)

FIGURE: 1 / 5

Cathepsin B Antibody (PA5-17006) in WB

Western blot analysis was performed on whole cell extracts (30 µg lysate) of T-47D (Lane 1), MDA-MB-231 (Lane 2) and THP-1 (Lane 3). The blot was probed with anti-Cathepsin B Rabbit Polyclonal Antibody (Product # PA5-17006, 1:500 dilution) and detected by chemiluminescence using Goat anti Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 37 kDa band corresponding to Cathepsin B was detected across the cell lines tested.

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Immunogen image

Immunogen Image Cathepsin B Polyclonal Antibody

Product Details

PA5-17006

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues surrounding Gly60 of human cathepsin B

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

26 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_10984870

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

Cathepsin B is a lysosomal cysteine protease that has been implicated in the pathogenesis of rheumatoid arthritis, muscular dystrophy and tumor metastasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: amyloid precursor protein secretase; APP secretase; APPS; Cathepsin B; Cathepsin B1; cysteine protease

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Gene Aliases: APPS; CPSB; CTSB

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UniProt ID: (Human) P07858

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Entrez Gene ID: (Human) 1508

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Function(s)

cysteine-type endopeptidase activity serine-type endopeptidase activity protein binding collagen binding peptidase activity cysteine-type peptidase activity kininogen binding peptide binding proteoglycan binding protein self-association

Process(es)

toll-like receptor signaling pathway proteolysis autophagy spermatogenesis skeletal muscle tissue development response to wounding response to glucose response to organic cyclic compound response to amine collagen catabolic process epithelial cell differentiation regulation of apoptotic process response to peptide hormone response to ethanol decidualization viral entry into host cell regulation of catalytic activity proteolysis involved in cellular protein catabolic process negative regulation of cell death response to interleukin-4 cellular response to mechanical stimulus cellular response to thyroid hormone stimulus

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Cathepsin B Polyclonal Antibody

Cathepsin B Antibody (PA5-17006) in WB

Product Details

PA5-17006

Western Blot (WB)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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