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Invitrogen

Catalase Polyclonal Antibody

1 Published Figure
2 References
View all (46) Catalase antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Catalase Polyclonal Antibody

  • Antibody Testing Data (5)
  • Published Figures (1)
Catalase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Catalase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 6

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Catalase Antibody (PA5-18531) in IHC (P)

Immunohistochemistry analysis of Catalase in human spleen. Samples were incubated with Catalase polyclonal antibody (Product # PA5-18531) using a dilution of 2 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Catalase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Catalase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Catalase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Catalase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Catalase Antibody in Western Blot (WB)
Catalase Antibody in Western Blot (WB)
Catalase Polyclonal Antibody

Product Details

PA5-18531

Applications
Tested Dilution
Publications

Western Blot (WB)

0.003-0.01 µg/mL
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

4-6 µg/mL
-

Immunocytochemistry (ICC/IF)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse

Published species

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide sequence (DKYNAEKPKNAIHT) corresponding to the internal amino acids of CAT (aa 498-511).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10980818

Product Specific Information

This antibody is predicted to react with canine based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Target Information

Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Catalase; catalase 1; CTA1; HGNC:1516; MGC138422; MGC138424

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Gene Aliases: 2210418N07; Cas-1; Cas1; CAT; Cs-1

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UniProt ID: (Human) P04040, (Mouse) P24270

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Entrez Gene ID: (Human) 847, (Mouse) 12359

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Function(s)
aminoacylase activity catalase activity receptor binding antioxidant activity oxidoreductase activity, acting on peroxide as acceptor enzyme binding heme binding protein homodimerization activity metal ion binding NADP binding peroxidase activity oxidoreductase activity
Process(es)
response to reactive oxygen species osteoblast differentiation ureteric bud development response to hypoxia purine nucleotide catabolic process triglyceride metabolic process aging cholesterol metabolic process aerobic respiration response to light intensity UV protection response to ozone response to lead ion positive regulation of phosphatidylinositol 3-kinase signaling response to activity response to inactivity hemoglobin metabolic process negative regulation of NF-kappaB transcription factor activity response to estradiol response to insulin response to vitamin A response to vitamin E response to L-ascorbic acid response to drug response to hydrogen peroxide hydrogen peroxide catabolic process negative regulation of apoptotic process response to ethanol response to cadmium ion positive regulation of NF-kappaB transcription factor activity protein tetramerization protein homotetramerization positive regulation of cell division response to hyperoxia response to fatty acid cellular response to growth factor stimulus response to phenylpropanoid cellular oxidant detoxification kidney development response to oxidative stress oxidation-reduction process
It has to be done as per old AB suggested Products section.
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