Invitrogen

Catalase Polyclonal Antibody

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Datasheet
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Datasheet
Protocols
Questions & Answers
Catalase Polyclonal Antibody

Product Details

PA5-119010

Applications
Tested Dilution
Publications

Western Blot (WB)

0.01-2 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

5-20 µg/mL
-

Immunocytochemistry (ICC/IF)

5-20 µg/mL
-

Flow Cytometry (Flow)

20 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein Catalase. The antigen corresponds to amino acid range 401-523 of the target protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2903510

Target Information

Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Catalase; catalase 1; CTA1; HGNC:1516; MGC138422; MGC138424

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Gene Aliases: 2210418N07; Cas-1; Cas1; CAT; Cat01; Catl; Cs-1; CS1

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UniProt ID: (Human) P04040, (Rat) P04762, (Mouse) P24270

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Entrez Gene ID: (Human) 847, (Rat) 24248, (Mouse) 12359

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Function(s)
aminoacylase activity catalase activity receptor binding antioxidant activity oxidoreductase activity, acting on peroxide as acceptor enzyme binding heme binding protein homodimerization activity metal ion binding NADP binding peroxidase activity oxidoreductase activity
Process(es)
response to reactive oxygen species osteoblast differentiation ureteric bud development response to hypoxia purine nucleotide catabolic process triglyceride metabolic process aging cholesterol metabolic process aerobic respiration response to light intensity UV protection response to ozone response to lead ion positive regulation of phosphatidylinositol 3-kinase signaling response to activity response to inactivity hemoglobin metabolic process negative regulation of NF-kappaB transcription factor activity response to estradiol response to insulin response to vitamin A response to vitamin E response to L-ascorbic acid response to drug response to hydrogen peroxide hydrogen peroxide catabolic process negative regulation of apoptotic process response to ethanol response to cadmium ion positive regulation of NF-kappaB transcription factor activity protein tetramerization protein homotetramerization positive regulation of cell division response to hyperoxia response to fatty acid cellular response to growth factor stimulus response to phenylpropanoid cellular oxidant detoxification kidney development response to oxidative stress response to radiation response to UV response to toxic substance oxidation-reduction process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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