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Invitrogen
Cardiac Troponin C Polyclonal Antibody
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Product Details
PA5-95994
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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RRID
Product Specific Information
Immunogen sequence: MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVMRMLGQ NPTPEELQEM IDEVDEDGSG TVDFDEFLVM MVRCMKDDSK GKSEEELSDL FRMFDKNADG YIDLDELKIM LQATGETITE DDIEELMKDG DKNNDGRIDY DEFLEFMKGV; Positive Samples: Mouse heart, Mouse lung, Mouse skeletal muscle
Target Information
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: cardiac 3; Cardiac troponin I; CMD1FF; CMD2A; CMH7; MGC116817; RCM1; TN-C; Tn1; Tni; TNN I3; TNNC 1; TNNI3; troponin C, cardiac/slow skeletal; Troponin C, slow skeletal and cardiac muscles; Troponin I; Troponin I cardiac; TroponinI
Gene Aliases: AI874626; cTnC; cTnI; TnC; Tncc; Tnnc1
UniProt ID: (Mouse) P19123
Entrez Gene ID: (Rat) 290561, (Mouse) 21924
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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