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Invitrogen
Cardiac Troponin C Polyclonal Antibody
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Product Details
PA5-80171
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Skeletal Muscle Tissue. IHC: Rat Cardiac Muscle Tissue.
Target Information
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: cardiac 3; cardiac troponin C; Cardiac troponin I; CMD1FF; CMD2A; CMH7; MGC116817; RCM1; slow twitch skeletal/cardiac muscle troponin C; TN-C; Tn1; Tni; TNN I3; TNNC 1; TNNI3; troponin C type 1 (slow); troponin C, cardiac/slow skeletal; Troponin C, slow skeletal and cardiac muscles; troponin C1, slow; Troponin I; Troponin I cardiac; TroponinI
Gene Aliases: AI874626; CMD1Z; CMH13; cTnC; cTnI; TN-C; TNC; Tncc; TNNC; TNNC1
UniProt ID: (Human) P63316, (Mouse) P19123
Entrez Gene ID: (Human) 7134, (Rat) 290561, (Mouse) 21924
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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