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  • Primary Antibodies ›
  • Carboxypeptidase B2 Antibodies

Invitrogen

Carboxypeptidase B2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (11A4)

View all (21) Carboxypeptidase B2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Carboxypeptidase B2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (11A4)

Product Details

MA5-54538

Applications
Tested Dilution
Publications

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Alpaca / VHH

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

11A4

Immunogen

Recombinant Human CPB2/TAFI.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Metal-chelate chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_3666788

Product Specific Information

Compatible with Direct ELISA

Target Information

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: carboxypeptidase B-like protein; Carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase R; Carboxypeptidase U; CPU; pCPB; Plasma carboxypeptidase B; TAFI; Thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor

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Gene Aliases: CPB2; CPU; PCPB; TAFI

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UniProt ID: (Human) Q96IY4

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Entrez Gene ID: (Human) 1361

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Function(s)
metallocarboxypeptidase activity zinc ion binding
Process(es)
positive regulation of extracellular matrix constituent secretion proteolysis blood coagulation response to heat negative regulation of plasminogen activation response to drug fibrinolysis negative regulation of fibrinolysis cellular response to glucose stimulus liver regeneration negative regulation of hepatocyte proliferation
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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