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Invitrogen
Carboxypeptidase B2 Monoclonal Antibody (5081)
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Product Details
MA1-43026
Species Reactivity
Host/Isotype
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Type
Clone
Immunogen
Conjugate
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Product Specific Information
MA1-43026 detects TAFI in human samples.
MA1-43026 has successfully been used in Western blot and ELISA applications.
MA1-43026 was derived from human TAFI.
Target Information
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: carboxypeptidase B-like protein; Carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase R; Carboxypeptidase U; CPU; pCPB; Plasma carboxypeptidase B; TAFI; Thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
Gene Aliases: CPB2; CPU; PCPB; TAFI
UniProt ID: (Human) Q96IY4
Entrez Gene ID: (Human) 1361
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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