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  • Primary Antibodies ›
  • Calcitonin Receptor Antibodies

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Calcitonin receptor Polyclonal Antibody

View all (15) Calcitonin Receptor antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Calcitonin receptor Polyclonal Antibody

Calcitonin receptor Polyclonal Antibody

Product Details

BS-10516R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Calcitonin receptor, amino acids 1-100.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes. The Calcitonin Receptor has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Calcitonin receptor; COPT1; CT receptor; CT-R; hCTR1

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Gene Aliases: CALCR; CRT; CT-R; CTR; CTR1

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UniProt ID: (Human) P30988

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Entrez Gene ID: (Human) 799

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Function(s)
receptor activity calcitonin receptor activity protein binding protein transporter activity calcitonin binding
Process(es)
cell surface receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway activation of adenylate cyclase activity protein transport positive regulation of cAMP biosynthetic process receptor internalization positive regulation of adenylate cyclase activity response to glucocorticoid protein localization to plasma membrane
It has to be done as per old AB suggested Products section.
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