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Invitrogen
CXCL12 beta (SDF-1 beta) Polyclonal Antibody, Biotin, PeproTech®
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FIGURE: 1 / 3
CXCL12 beta (SDF-1 beta) Antibody (500-P87BGBT-25UG) in ELISA
Product Details
500-P87BGBT-25UG
Species Reactivity
Published species
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Immunogen
Conjugate
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Product Specific Information
AA Sequence of recombinant protein: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM.
Preparation: Produced from sera of goats immunized with highly pure Recombinant Human SDF-1beta (CXCL12). Anti-Human SDF-1beta (CXCL12)-specific antibody was purified by affinity chromatography and then biotinylated.
Sandwich ELISA: To detect Human SDF-1beta by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.25-1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human SDF-1beta (500-P87BG) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human SDF-1beta.
Western Blot: To detect Human SDF-1beta by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 µg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human SDF-1beta is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
500-P87BGBT-1MG will be provided as 2 x 500 µg
Target Information
CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 12; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; CXC; CXC motif chemokine; CXCL; Intercrine reduced in hepatomas; IRH; PBSF; Pre-B cell growth-stimulating factor; SDF-1; sdf-1 beta; Stromal cell-derived factor 1
Gene Aliases: CXCL12; IRH; PBSF; SCYB12; SDF1; SDF1A; SDF1B; TLSF; TPAR1
UniProt ID: (Human) P48061
Entrez Gene ID: (Human) 6387
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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