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Invitrogen
CXCL12 alpha (SDF-1 alpha) Polyclonal Antibody, Biotin, PeproTech®
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FIGURE: 1 / 3
CXCL12 alpha (SDF-1 alpha) Antibody (500-P315BT-25UG) in ELISA
Product Details
500-P315BT-25UG
Species Reactivity
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Immunogen
Conjugate
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Product Specific Information
AA Sequence of recombinant protein: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNK.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Rat SDF-1alpha (CXCL12). Anti-Rat SDF-1alpha (CXCL12)-specific antibody was purified by affinity chromatography and then biotinylated.
Sandwich ELISA: To detect Rat SDF-1alpha by sandwich ELISA (using 100 µL/well), a concentration of 0.25-1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Rat SDF-1alpha (500-P315) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Rat SDF-1alpha.
Western Blot: To detect Rat SDF-1alpha by Western Blot analysis, this antibody can be used at a concentration of 0.1-0.2 µg/mL. When used in conjunction with compatible development reagents, the detection limit for Recombinant Rat SDF-1alpha is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
500-P315BT-1MG will be provided as 2 x 500 µg
Target Information
CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; CXCL; H-SDF-1-alpha; SDF 1 a; SDF 1 alpha; SDF 1α; SDF-1 gamma; SDF1 alpha; SDF1α; stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma
Gene Aliases: Sdf1
Entrez Gene ID: (Rat) 24772
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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