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  • Primary Antibodies ›
  • CXCL12 Antibodies
Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.

Invitrogen

CXCL12 Recombinant Superclonal™ Antibody (1HCLC)

View all (27) CXCL12 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite CXCL12 Recombinant Superclonal™ Antibody (1HCLC)

  • Antibody Testing Data (1)
CXCL12 Antibody in ELISA (ELISA)
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CXCL12 Antibody in ELISA (ELISA)
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CXCL12 Antibody (711345) in ELISA

Indirect ELISA analysis of Anti-CXCL12 Recombinant Rabbit Superclonal™ Antibody (Product # 711345) was performed by coating recombinant human CXCL12 protein standard at concentrations ranging from 0.24 ng/mL to 250 ng/mL onto a plate. The coated protein was bound by Anti-CXCL12 Recombinant Rabbit Superclonal™ Antibody at 1 µg/mL and was detected using Goat anti-Rabbit IgG (H+L) secondary antibody, HRP-conjugate (Product # G-21234, 1:5000 dilution). The plate was developed using stabilized chromogen solution, TMB+H2O2 (Product # SB01). The ... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CXCL12 Antibody in ELISA (ELISA)
CXCL12 Recombinant Superclonal™ Antibody (1HCLC)

Product Details

711345

Applications
Tested Dilution
Publications

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Superclonal

Type

Antibody

Clone

1HCLC

Immunogen

Protein corresponding to Human CXCL12 (aa 22-88)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2633165

Product Specific Information

This antibody is predicted to react with Monkey, cat, Pig and Horse.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.

Target Information

CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AI174028; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 12; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; CXC; CXC motif chemokine; CXCL; hIRH; hSDF-1; Intercrine reduced in hepatomas; IRH; PBSF; Pre-B cell growth-stimulating factor; SDF-1; SDF-1a; SDF-1b; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; TLSF-a; TLSF-b; Tlsfa; Tlsfb

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Gene Aliases: CXCL12; IRH; PBSF; SCYB12; SDF1; SDF1A; SDF1B; TLSF; TPAR1

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UniProt ID: (Human) P48061

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Entrez Gene ID: (Human) 6387

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Function(s)
receptor binding chemokine activity growth factor activity chemoattractant activity chemokine receptor binding CXCR chemokine receptor binding
Process(es)
response to hypoxia neuron migration positive regulation of endothelial cell proliferation cellular calcium ion homeostasis chemotaxis immune response cell adhesion signal transduction G-protein coupled receptor signaling pathway axon guidance blood circulation regulation of actin polymerization or depolymerization adult locomotory behavior response to radiation response to heat response to mechanical stimulus response to virus telencephalon cell migration organ regeneration positive regulation of dopamine secretion response to peptide hormone positive regulation of cell adhesion positive regulation of axon extension involved in axon guidance positive chemotaxis induction of positive chemotaxis cell chemotaxis chemokine-mediated signaling pathway positive regulation of monocyte chemotaxis positive regulation of calcium ion import negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of leukocyte tethering or rolling negative regulation of leukocyte apoptotic process positive regulation of T cell migration
It has to be done as per old AB suggested Products section.
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