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  • COMP Antibodies

Invitrogen

COMP Monoclonal Antibody (4H6G10D2)

View all (10) COMP antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite COMP Monoclonal Antibody (4H6G10D2)

COMP Monoclonal Antibody (4H6G10D2)

Product Details

MA5-30266

Applications
Tested Dilution
Publications

ELISA (ELISA)

1:250-1:2,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

4H6G10D2

Immunogen

Recombinant Human COMP protein (Met1-Ala757)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2786021

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human COMP/THBS5.

Target Information

COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple); COMP; MGC131819; MGC149768; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); Thrombospondin-5; Thrombospondin5; TSP 5; TSP5

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Gene Aliases: COMP; EDM1; EPD1; MED; PSACH; THBS5; TSP5

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UniProt ID: (Human) P49747

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Entrez Gene ID: (Human) 1311

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Function(s)
protease binding extracellular matrix structural constituent calcium ion binding protein binding collagen binding heparin binding heparan sulfate proteoglycan binding
Process(es)
skeletal system development growth plate cartilage development apoptotic process cell adhesion organ morphogenesis extracellular matrix organization negative regulation of apoptotic process limb development
It has to be done as per old AB suggested Products section.
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