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Invitrogen
CNTF Monoclonal Antibody (34738)
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Product Details
MA5-23730
Species Reactivity
Published species
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Storage conditions
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RRID
Product Specific Information
In sandwich ELISAs, less than 3% cross-reactivity with recombinant human CNTF is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Endoxin level is <1.0 EU per 1 µg of the antibody by the LAL method.
Target Information
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ciliary neurotrophic factor; ciliary neurotropic factor; CNTF; H-CNTF
Gene Aliases: Cntf
UniProt ID: (Rat) P20294
Entrez Gene ID: (Rat) 25707
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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