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  • Primary Antibodies ›
  • CHI3L1 Antibodies

Invitrogen

CHI3L1 Recombinant Rabbit Monoclonal Antibody (101)

View all (19) CHI3L1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite CHI3L1 Recombinant Rabbit Monoclonal Antibody (101)

Product Details

MA5-43079

Applications
Tested Dilution
Publications

ELISA (ELISA)

1:5,000-1:10,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

101

Immunogen

Recombinant Human CHI3L1/YKL40 protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912219

Product Specific Information

Specificity: Human CHI3L1/YKL40

Target Information

Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 39 kDa synovial protein; Cartilage glycoprotein 39; CGP-39; CGP39; Chitinase 3 like protein 1CGP 39; chitinase 3-like 1 (cartilage glycoprotein-39); Chitinase-3-like protein 1; DKFZp686N19119; FLJ38139; hCGP39; YKL-40

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Gene Aliases: ASRT7; CGP-39; CHI3L1; GP-39; GP39; HC-gp39; hCGP-39; HCGP-3P; YKL-40; YKL40; YYL-40

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UniProt ID: (Human) P36222

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Entrez Gene ID: (Human) 1116

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Function(s)
chitinase activity extracellular matrix structural constituent chitin binding carbohydrate binding
Process(es)
carbohydrate metabolic process chitin catabolic process apoptotic process inflammatory response activation of NF-kappaB-inducing kinase activity response to mechanical stimulus positive regulation of peptidyl-threonine phosphorylation lung development response to tumor necrosis factor positive regulation of angiogenesis cartilage development positive regulation of protein kinase B signaling positive regulation of ERK1 and ERK2 cascade response to interleukin-1 response to interleukin-6 cellular response to interleukin-1 cellular response to tumor necrosis factor interleukin-8 secretion
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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