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  • CHI3L1 Antibodies

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CHI3L1 Polyclonal Antibody, MaxPab™

View all (19) CHI3L1 antibodies

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Questions & Answers

Cite CHI3L1 Polyclonal Antibody, MaxPab™

  • Antibody Testing Data (1)
CHI3L1 Antibody in Western Blot (WB)
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CHI3L1 Antibody in Western Blot (WB)
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CHI3L1 Antibody (H00001116-D01P) in WB

Western Blot analysis of CHI3L1 expression in transfected 293T cell line (H00001116-T02) by CHI3L1 MaxPab polyclonal antibody.

Lane 1: CHI3L1 transfected lysate(42.60 KDa).
Lane 2: Non-transfected lysate.
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CHI3L1 Antibody in Western Blot (WB)
CHI3L1 Polyclonal Antibody, MaxPab™

Product Details

H00001116-D01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CHI3L1 (AAH08568.1, 1 a.a. approximately 383 a.a) full-length human protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MGVKASQTGF VVLVLLQCCS AYKLVCYYTS WSQYREGDGS CFPDALDRFL CTHIIYSFAN ISNDHIDTWE WNDVTLYGML NTLKNRNPNL KTLLSVGGWN FGSQRFSKIA SNTQSRRTFI KSVPPFLRTH GFDGLDLAWL YPGRRDKQHF TTLIKEMKAE FIKEAQPGKK QLLLSAALSA GKVTIDSSYD IAKISQHLDF ISIMTYDFHG AWRGTTGHHS PLFRGQEDAS PDRFSNTDYA VGYMLRLGAP ASKLVMGIPT FGRSFTLASS ETGVGAPISG PGIPGRFTKE AGTLAYYEIC DFLRGATVHR ILGQQVPYAT KGNQWVGYDD QESVKSKVQY LKDRQLAGAM VWALDLDDFQ GSFCGQDLRF PLTNAIKDAL AAT

Target Information

Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 39 kDa synovial protein; Cartilage glycoprotein 39; CGP-39; CGP39; Chitinase 3 like protein 1CGP 39; chitinase 3-like 1 (cartilage glycoprotein-39); Chitinase-3-like protein 1; DKFZp686N19119; FLJ38139; hCGP39; YKL-40

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Gene Aliases: ASRT7; CGP-39; CHI3L1; GP-39; GP39; HC-gp39; hCGP-39; HCGP-3P; YKL-40; YKL40; YYL-40

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UniProt ID: (Human) P36222

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Entrez Gene ID: (Human) 1116

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Function(s)
chitinase activity extracellular matrix structural constituent chitin binding carbohydrate binding
Process(es)
carbohydrate metabolic process chitin catabolic process apoptotic process inflammatory response activation of NF-kappaB-inducing kinase activity response to mechanical stimulus positive regulation of peptidyl-threonine phosphorylation lung development response to tumor necrosis factor positive regulation of angiogenesis cartilage development positive regulation of protein kinase B signaling positive regulation of ERK1 and ERK2 cascade response to interleukin-1 response to interleukin-6 cellular response to interleukin-1 cellular response to tumor necrosis factor interleukin-8 secretion
It has to be done as per old AB suggested Products section.
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