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  • CHI3L1 Antibodies

Proteintech

CHI3L1 Polyclonal Antibody

16 References
View all (19) CHI3L1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite CHI3L1 Polyclonal Antibody

  • Antibody Testing Data (4)
CHI3L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CHI3L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CHI3L1 Antibody (12036-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver tissue slide using 12036-1-AP ( CHI3L1 Antibody) at dilution of 1:200 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CHI3L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CHI3L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CHI3L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CHI3L1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CHI3L1 Polyclonal Antibody

Product Details

12036-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

-
View 5 publications 5 publications

Immunohistochemistry (IHC)

-
View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400
-

Immunocytochemistry (ICC/IF)

-
View 5 publications 5 publications
Product Specifications

Species Reactivity

Human, Mouse

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CHI3L1 Fusion Protein Ag2710 (34-383 aa encoded by BC008568)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: YREGDGSCF PDALDRFLCT HIIYSFANIS NDHIDTWEWN DVTLYGMLNT LKNRNPNLKT LLSVGGWNFG SQRFSKIASN TQSRRTFIKS VPPFLRTHGF DGLDLAWLYP GRRDKQHFTT LIKEMKAEFI KEAQPGKKQL LLSAALSAGK VTIDSSYDIA KISQHLDFIS IMTYDFHGAW RGTTGHHSPL FRGQEDASPD RFSNTDYAVG YMLRLGAPAS KLVMGIPTFG RSFTLASSET GVGAPISGPG IPGRFTKEAG TLAYYEICDF LRGATVHRIL GQQVPYATKG NQWVGYDDQE SVKSKVQYLK DRQLAGAMVW ALDLDDFQGS FCGQDLRFPL TNAIKDALAA T (34-383 aa encoded by BC008568)

Target Information

Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 39 kDa synovial protein; Breast regression protein 39; BRP39 protein; Cartilage glycoprotein 39; CGP-39; CGP39; Chitinase 3 like protein 1CGP 39; chitinase 3-like 1; chitinase 3-like 1 (cartilage glycoprotein-39); Chitinase-3-like protein 1; DKFZp686N19119; FLJ38139; GP-39; hCGP39; YKL-40

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Gene Aliases: ASRT7; AW208766; Brp39; CGP-39; CHI3L1; Chil1; GP-39; GP39; HC-gp39; hCGP-39; HCGP-3P; YKL-40; YKL40; YYL-40

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UniProt ID: (Human) P36222, (Mouse) Q61362

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Entrez Gene ID: (Human) 1116, (Mouse) 12654

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Function(s)
chitinase activity extracellular matrix structural constituent chitin binding carbohydrate binding hydrolase activity, hydrolyzing O-glycosyl compounds
Process(es)
carbohydrate metabolic process chitin catabolic process apoptotic process inflammatory response activation of NF-kappaB-inducing kinase activity positive regulation of peptidyl-threonine phosphorylation lung development positive regulation of angiogenesis positive regulation of protein kinase B signaling positive regulation of ERK1 and ERK2 cascade interleukin-8 secretion response to mechanical stimulus response to tumor necrosis factor cartilage development response to interleukin-1 response to interleukin-6 cellular response to interleukin-1 cellular response to tumor necrosis factor
It has to be done as per old AB suggested Products section.
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