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Invitrogen
CFHR5 Monoclonal Antibody (3E1E10)
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FIGURE: 1 / 7
CFHR5 Antibody (MA5-31677) in ELISA
Product Details
MA5-31677
Species Reactivity
Host/Isotype
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Conjugate
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Product Specific Information
MA5-31677 has been tested in indirect ELISA.
Target Information
This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: complement factor H-related 5; Complement factor H-related protein 5; factor H-related protein 5; FHR-5
Gene Aliases: CFHL5; CFHR5; CFHR5D; FHR-5; FHR5
UniProt ID: (Human) Q9BXR6
Entrez Gene ID: (Human) 81494
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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