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  • CD70 Antibodies

NeoBiotechnologies

CD70/TNFSF7 (Activated T- and B-Lymphocyte Marker) Monoclonal Antibody (BU69)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite CD70/TNFSF7 (Activated T- and B-Lymphocyte Marker) Monoclonal Antibody (BU69)

CD70/TNFSF7 (Activated T- and B-Lymphocyte Marker) Monoclonal Antibody (BU69)

Product Details

970-MSM1-P1ABX

Applications
Tested Dilution
Publications

Immunohistochemistry (Frozen) (IHC (F))

1-2 µg/mL
-

Immunocytochemistry (ICC/IF)

1-2 µg/mL
-

Flow Cytometry (Flow)

1-2 µg/10^6 cells
-

ELISA (ELISA)

Assay-dependent
-

Immunoprecipitation (IP)

1-2 µg
-

Functional Assay (Functional)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

BU69

Immunogen

Human WM-1 (Waldenstrom s macroglobulinemia) cell line
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD27 ligand; CD27-L; CD70; CD70 antigen; Ki-24 antigen; surface antigen CD70; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8A; Tumor necrosis factor ligand superfamily member 7

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Gene Aliases: CD27L; CD27LG; CD70; TNFSF7; TNLG8A

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UniProt ID: (Human) P32970

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Entrez Gene ID: (Human) 970

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Function(s)
protease binding receptor binding cytokine activity tumor necrosis factor receptor binding protein binding
Process(es)
immune response signal transduction cell-cell signaling cell proliferation tumor necrosis factor-mediated signaling pathway extrinsic apoptotic signaling pathway
It has to be done as per old AB suggested Products section.
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