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  • Primary Antibodies ›
  • CD154 (CD40 Ligand) Antibodies

Abnova

CD40LG Monoclonal Antibody (3G3)

View all (84) CD154 (CD40 Ligand) antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite CD40LG Monoclonal Antibody (3G3)

CD40LG Monoclonal Antibody (3G3)

Product Details

H00000959-M08

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-

ELISA (ELISA)

10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

3G3

Immunogen

Recombinant Flag/His fusion protein corresponding to amino acids 116-261 of human CD40LG.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD154; CD40 antigen ligand; CD40 ligand; CD40-L; H-CD-40-L; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-cell antigen Gp39; TNF-related activation protein; TRAP; tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor ligand superfamily member 5

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Gene Aliases: CD154; CD40L; CD40LG; gp39; hCD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP

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UniProt ID: (Human) P29965

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Entrez Gene ID: (Human) 959

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Function(s)
cytokine activity tumor necrosis factor receptor binding CD40 receptor binding protein binding
Process(es)
inflammatory response leukocyte cell-cell adhesion activation of JUN kinase activity platelet activation B cell differentiation T cell costimulation positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-4 production tumor necrosis factor-mediated signaling pathway B cell proliferation positive regulation of T cell proliferation negative regulation of apoptotic process isotype switching immunoglobulin secretion regulation of immune response regulation of immunoglobulin secretion positive regulation of NF-kappaB transcription factor activity positive regulation of endothelial cell apoptotic process
It has to be done as per old AB suggested Products section.
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