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Invitrogen
CD4 Monoclonal Antibody (RIV6)
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FIGURE: 1 / 2
CD4 Antibody (MA1-7631) in IHC
Product Details
MA1-7631
Species Reactivity
Published species
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Conjugate
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Product Specific Information
MA1-7631 detects CD4 from human, rat and mouse samples.
MA1-7631 has been successfully used in ELISA, flow cytometry, immunoprecipitation and immunohistochemistry procedures.
The MA1-7631 immunogen is whole T cells.
Store at 4°C for short term. For long term storage, store at -80°C.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; CD4 receptor; cd4a; fCD4; Leu-3; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); W3/25 antigen
Gene Aliases: CD4; CD4mut; L3T4; Ly-4; p55; W3/25
UniProt ID: (Human) P01730, (Rat) P05540, (Mouse) P06332
Entrez Gene ID: (Human) 920, (Rat) 24932, (Mouse) 12504
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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