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Invitrogen
CD275 (B7-H2) Chimeric Recombinant Rabbit Monoclonal Antibody (HK5.3)
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FIGURE: 1 / 2
CD275 (B7-H2) Chimeric Antibody (MA5-48098) in ELISA
Product Details
MA5-48098
Species Reactivity
Host/Isotype
Expression System
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Clone
Immunogen
Conjugate
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Product Specific Information
Specificity: This antibody specifically binds to mouse ICOSL and competes with binding of ICOS.
Target Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: B7 homolog 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD275; ICOS ligand; LICOS
Gene Aliases: AU044799; B7-H2; B7h; B7h2; B7RP-1; B7rp1; BG071784; GI50; GL50; GL50-B; ICOS-L; Icosl; Icoslg; LICOS; Ly115l; mKIAA0653
UniProt ID: (Mouse) Q9JHJ8
Entrez Gene ID: (Mouse) 50723
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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