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CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Monoclonal Antibody (BCMA/7254)

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Monoclonal Antibody (BCMA/7254)

  • Antibody Testing Data (2)
CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 2

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CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Antibody (608-MSM4-P1ABX) in IHC (P)

Formalin-fixed, paraffin-embedded human colon carcinoma stained with CD269/TNFRSF17 Mouse Monoclonal Antibody (BCMA/7254). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Antibody in Western Blot (WB)
CD269/TNFRSF17/BCMA (B-Cell Maturation Protein) Monoclonal Antibody (BCMA/7254)

Product Details

608-MSM4-P1ABX

Applications
Tested Dilution
Publications

Western Blot (WB)

2-4 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2, kappa

Class

Monoclonal

Type

Antibody

Clone

BCMA/7254

Immunogen

Recombinant human CD269 protein fragment (around aa 1-184).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control:NAMALWA or Daudi cells. Tonsil or gastric carcinoma (IHC).

Cellular Location: Cell surface.

Target Information

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: B cell maturation antigen; B-cell maturation factor; B-cell maturation protein; CD269; Tumor necrosis factor receptor superfamily member 17; tumor necrosis factor receptor superfamily, member 17

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Gene Aliases: BCM; BCMA; CD269; TNFRSF13A; TNFRSF17

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UniProt ID: (Human) Q02223

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Entrez Gene ID: (Human) 608

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Function(s)
receptor activity
Process(es)
adaptive immune response lymphocyte homeostasis signal transduction multicellular organism development cell proliferation tumor necrosis factor-mediated signaling pathway
It has to be done as per old AB suggested Products section.
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