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Invitrogen
CD267 (TACI) Polyclonal Antibody, PeproTech®
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FIGURE: 1 / 3
CD267 (TACI) Antibody (500-P166G-1MG) in ELISA
Product Details
500-P166G-1MG
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Purification
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RRID
Product Specific Information
AA Sequence of recombinant protein: SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQV.
Preparation: Produced from sera of goats immunized with highly pure Recombinant Human TACI. Anti-Human TACI-specific antibody was purified by affinity chromatography employing an immobilized Human TACI matrix.
Sandwich ELISA: To detect Human TACI by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human TACI (500-P166GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human TACI.
Western Blot: To detect Human TACI by Western Blot analysis this antibody can be used at a concentration of 0.1- 0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human TACI is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Target Information
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CD267; Transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B; Tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13B
Gene Aliases: CD267; CVID; CVID2; IGAD2; RYZN; TACI; TNFRSF13B; TNFRSF14B
UniProt ID: (Human) O14836
Entrez Gene ID: (Human) 23495
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