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  • CD171 (L1CAM) Antibodies

NeoBiotechnologies

CD171/NCAM-L1 (L1 Cell Adhesion Molecule) Recombinant Rabbit Monoclonal Antibody (L1CAM/9146R)

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Cite CD171/NCAM-L1 (L1 Cell Adhesion Molecule) Recombinant Rabbit Monoclonal Antibody (L1CAM/9146R)

  • Antibody Testing Data (1)
CD171/NCAM-L1 (L1 Cell Adhesion Molecule) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CD171/NCAM-L1 (L1 Cell Adhesion Molecule) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CD171/NCAM-L1 (L1 Cell Adhesion Molecule) Antibody (3897-RBM7-P1ABX) in IHC (P)

Formalin-fixed, paraffin-embedded human brain stained with CD171 Recombinant Rabbit Monoclonal Antibody (L1CAM/9146R). Inset: PBS instead of primary antibody; secondary only negative control. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CD171/NCAM-L1 (L1 Cell Adhesion Molecule) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CD171/NCAM-L1 (L1 Cell Adhesion Molecule) Recombinant Rabbit Monoclonal Antibody (L1CAM/9146R)

Product Details

3897-RBM7-P1ABX

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

L1CAM/9146R

Immunogen

Recombinant full-length human L1CAM protein
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS

Contains

no preservative

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Dry ice (international)

Product Specific Information

Positive Control:Human brain total lysate (WB). PC12 and Neuro-2A (ICC).

Cellular Location: Cytoplasm. Cell surface.

Target Information

L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: antigen identified by monoclonal antibody R1; CD 171; CD171; CD171 molecule; N-CAM-L1; Neural cell adhesion molecule L1; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM

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Gene Aliases: CAML1; CD171; HSAS; HSAS1; L1CAM; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1

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UniProt ID: (Human) P32004

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Entrez Gene ID: (Human) 3897

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Process(es)
chemotaxis cell adhesion nervous system development axon guidance positive regulation of axon extension leukocyte migration
It has to be done as per old AB suggested Products section.
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