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  • Primary Antibodies ›
  • CD142 Antibodies

Invitrogen

CD142 Polyclonal Antibody

View all (8) CD142 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite CD142 Polyclonal Antibody

Product Details

PA1-43058

Applications
Tested Dilution
Publications

Western Blot (WB)

5-10 µg/mL
-

ELISA (ELISA)

5-10 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Sheep / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Human Tissue Factor.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

13.0 mg/mL

Purification

SDS-PAGE

Storage buffer

50% water with 50% glycerol

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2101346

Product Specific Information

PA1-43058 detects Tissue Factor in human samples.

PA1-43058 has successfully been used in Western blot and ELISA applications.

PA1-43058 was derived from human tissue factor.

Target Information

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD142; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); TF; Thromboplastin; Tissue factor

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Gene Aliases: CD142; F3; TF; TFA

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UniProt ID: (Human) P13726

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Entrez Gene ID: (Human) 2152

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Function(s)
protease binding serine-type endopeptidase activity cytokine receptor activity protein binding phospholipid binding
Process(es)
positive regulation of endothelial cell proliferation activation of plasma proteins involved in acute inflammatory response activation of blood coagulation via clotting cascade activation of cysteine-type endopeptidase activity involved in apoptotic process aging blood coagulation blood coagulation, extrinsic pathway response to temperature stimulus response to mechanical stimulus positive regulation of platelet-derived growth factor receptor signaling pathway positive regulation of smooth muscle cell migration protein processing cytokine-mediated signaling pathway positive regulation of cell migration response to estradiol response to lipopolysaccharide response to fluid shear stress positive regulation of angiogenesis positive regulation of positive chemotaxis positive regulation of protein kinase B signaling response to low-density lipoprotein particle cellular response to hydrogen peroxide
It has to be done as per old AB suggested Products section.
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