Bioss

CD14 Polyclonal Antibody

Name: CD14 Polyclonal Antibody
Brand: Bioss
SKU: BS-1192R

View all (206) CD14 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (2)

CD14 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 2

CD14 Antibody (BS-1192R) in IHC (P)

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-CD14 Polyclonal Antibody, Unconjugated (bs-1192R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Product Image Gallery

Immunogen image

Immunogen Image CD14 Polyclonal Antibody

Product Details

BS-1192R

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500

Immunocytochemistry (ICC/IF)

1:100-1:500

Flow Cytometry (Flow)

1:20

ELISA (ELISA)

1:500-1:1,000

Product Specifications

Species Reactivity

Dog, Human, Mouse, Sheep, Rabbit, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from mouse CD14, amino acids 201-300.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Bioinformatics

Protein Aliases: CD 14; CD14; CD14 antigen; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell-specific leucine-rich glycoprotein; sCD14; soluble CD14

View more View less

Gene Aliases: CD14

View more View less

UniProt ID: (Rabbit) Q28680, (Human) P08571, (Rat) Q63691, (Mouse) P10810

View more View less

Entrez Gene ID: (Rabbit) 100008983, (Human) 929, (Sheep) 443216, (Dog) 607076, (Rat) 60350, (Mouse) 12475

View more View less

Function(s)

lipopolysaccharide binding opsonin receptor activity protein binding peptidoglycan receptor activity lipoteichoic acid binding

Process(es)

response to molecule of bacterial origin inflammatory response response to heat response to magnesium ion response to lipopolysaccharide positive regulation of tumor necrosis factor production response to tumor necrosis factor innate immune response response to ethanol positive regulation of endocytosis positive regulation of cytokine secretion response to electrical stimulus cellular response to lipopolysaccharide cellular response to lipoteichoic acid MyD88-dependent toll-like receptor signaling pathway MyD88-independent toll-like receptor signaling pathway receptor-mediated endocytosis phagocytosis apoptotic process cell surface receptor signaling pathway I-kappaB kinase/NF-kappaB signaling lipopolysaccharide-mediated signaling pathway positive regulation of type I interferon production positive regulation of interferon-gamma production negative regulation of MyD88-independent toll-like receptor signaling pathway toll-like receptor 4 signaling pathway TRIF-dependent toll-like receptor signaling pathway toll-like receptor TLR1:TLR2 signaling pathway toll-like receptor TLR6:TLR2 signaling pathway necroptotic process cellular response to diacyl bacterial lipopeptide cellular response to triacyl bacterial lipopeptide apoptotic signaling pathway immune system process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

CD14 Polyclonal Antibody

CD14 Antibody (BS-1192R) in IHC (P)

Product Details

BS-1192R

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

ELISA (ELISA)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

References (0)

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!