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  • Eotaxin 3 Antibodies

Bioss

CCL26 Polyclonal Antibody

View all (15) Eotaxin 3 antibodies

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Datasheet
Protocols
Questions & Answers

Cite CCL26 Polyclonal Antibody

  • Antibody Testing Data (1)
CCL26 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CCL26 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CCL26 Antibody (BS-15513R) in IHC (P)

Paraformaldehyde-fixed, paraffin embedded rat ovary; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with CCL26 Polyclonal Antibody (bs-15513R) at 1:400 overnight at 4°C, followed by a SP kit and DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CCL26 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

BS-15513R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:400
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

Flow Cytometry (Flow)

1:20-1:100
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from rat CCL26.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C-C motif chemokine 26; CC chemokine IMAC; chemokine (C-C motif) ligand 26; chemokine N1; Eotaxin-3; Eotaxin3; Macrophage inflammatory protein 4-alpha; MGC126714; MIP-4-alpha; PRO242; SCYA26MIP-4-alpha; small inducible cytokine A26; small inducible cytokine subfamily A (Cys-Cys), member 26; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; UNQ216

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Gene Aliases: CCL26; Ccl26l; IMAC; MIP-4a; MIP-4alpha; SCYA26; TSC-1; UNQ216/PRO242

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UniProt ID: (Human) Q9Y258

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Entrez Gene ID: (Human) 10344, (Rat) 685958, (Mouse) 541307

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Function(s)
chemokine activity CCR chemokine receptor binding molecular_function
Process(es)
positive regulation of endothelial cell proliferation monocyte chemotaxis chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor signaling pathway cell-cell signaling positive regulation of cell migration neutrophil chemotaxis positive regulation of actin filament polymerization positive regulation of GTPase activity lymphocyte chemotaxis positive regulation of inflammatory response chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor biological_process cell chemotaxis
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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