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CCL23/Myeloid Progenitor Inhibitory Factor 1 Monoclonal Antibody (CCL23/4034)

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite CCL23/Myeloid Progenitor Inhibitory Factor 1 Monoclonal Antibody (CCL23/4034)

  • Antibody Testing Data (1)
CCL23/Myeloid Progenitor Inhibitory Factor 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CCL23/Myeloid Progenitor Inhibitory Factor 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CCL23/Myeloid Progenitor Inhibitory Factor 1 Antibody (6368-MSM4-P1) in IHC (P)

Formalin-fixed, paraffin-embedded human adrenal gland stained with CCL23 Mouse Monoclonal Antibody (CCL23/4034). HIER: Tris/EDTA, pH9.0, 45 min. 2°: HRP-polymer, 30 min. DAB, 5 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CCL23/Myeloid Progenitor Inhibitory Factor 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CCL23/Myeloid Progenitor Inhibitory Factor 1 Monoclonal Antibody (CCL23/4034)

Product Details

6368-MSM4-P1

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL
-

Peptide Array (Array)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2, kappa

Class

Monoclonal

Type

Antibody

Clone

CCL23/4034

Immunogen

Recombinant fragment (around aa1-120) of human CCL23 protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control: High levels in adult lung liver skeletal muscle and pancreas.

Cellular Location: Secreted.

Target Information

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C-C motif chemokine 23; C6 beta-chemokine; chemokine (C-C motif) ligand 23; Ck beta 8-1; CK-beta-8; CKB-8; Macrophage inflammatory protein 3; MIP-3; MIP-3CK-BETA-8; MPIF-1; MPIF-1Ckb-8-1; Myeloid progenitor inhibitory factor 1; small inducible cytokine subfamily A (Cys-Cys), member 23; Small-inducible cytokine A23

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Gene Aliases: CCL23; CK-BETA-8; Ckb-8; Ckb-8-1; CKb8; hmrp-2a; MIP-3; MIP3; MPIF-1; MPIF1; SCYA23

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UniProt ID: (Human) P55773

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Entrez Gene ID: (Human) 6368

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Function(s)
chemokine activity heparin binding CCR1 chemokine receptor binding
Process(es)
monocyte chemotaxis cellular calcium ion homeostasis chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor signaling pathway cell-cell signaling negative regulation of cell proliferation neutrophil chemotaxis positive regulation of GTPase activity lymphocyte chemotaxis positive regulation of inflammatory response chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor negative regulation of C-C chemokine binding
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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