OriGene

CAT Monoclonal Antibody (OTI3C3), TrueMAB™

Name: CAT Monoclonal Antibody (OTI3C3), TrueMAB\u2122
Brand: OriGene
SKU: TA502497

View all (46) Catalase antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (13)

CAT Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 13

CAT Antibody (TA502497) in ICC/IF

Anti-CAT mouse monoclonal antibody (TA502497) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CAT(RC210763).

CAT Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Immunogen image

Immunogen Image CAT Monoclonal Antibody (OTI3C3), TrueMAB™

Product Details

TA502497

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:500

Immunohistochemistry (Paraffin) (IHC (P))

1:150

Immunocytochemistry (ICC/IF)

1:100

Flow Cytometry (Flow)

Assay-dependent

Product Specifications

Species Reactivity

Dog, Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI3C3

Immunogen

Full length human recombinant protein of human CAT produced in HEK293T cell.

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.57 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Catalase; CTA1; HGNC:1516; MGC138422; MGC138424

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Gene Aliases: CAT

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UniProt ID: (Human) P04040, (Dog) O97492

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Entrez Gene ID: (Human) 847, (Dog) 403474

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Function(s)

aminoacylase activity catalase activity receptor binding antioxidant activity oxidoreductase activity, acting on peroxide as acceptor enzyme binding heme binding protein homodimerization activity metal ion binding NADP binding

Process(es)

response to reactive oxygen species osteoblast differentiation ureteric bud development response to hypoxia purine nucleotide catabolic process triglyceride metabolic process aging cholesterol metabolic process aerobic respiration response to light intensity UV protection response to ozone response to lead ion positive regulation of phosphatidylinositol 3-kinase signaling response to activity response to inactivity hemoglobin metabolic process negative regulation of NF-kappaB transcription factor activity response to estradiol response to insulin response to vitamin A response to vitamin E response to L-ascorbic acid response to drug response to hydrogen peroxide hydrogen peroxide catabolic process negative regulation of apoptotic process response to ethanol response to cadmium ion positive regulation of NF-kappaB transcription factor activity protein tetramerization protein homotetramerization positive regulation of cell division response to hyperoxia response to fatty acid cellular response to growth factor stimulus response to phenylpropanoid cellular oxidant detoxification oxidation-reduction process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CAT Monoclonal Antibody (OTI3C3), TrueMAB™

CAT Antibody (TA502497) in ICC/IF

Product Details

TA502497

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

References (0)

Bioinformatics

Performance Guarantee

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