Invitrogen

CACNB2 Polyclonal Antibody

Name: CACNB2 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-90894

View all (30) CACNB2 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (4)

CACNB2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 4

CACNB2 Antibody (PA5-90894) in IHC (P)

Immunohistochemistry analysis of CACNB2 in paraffin-embedded human colon carcinoma. Samples were incubated with CACNB2 Polyclonal antibody (Product # PA5-90894) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

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Immunogen image

Immunogen Image CACNB2 Polyclonal Antibody

Product Details

PA5-90894

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:200

ELISA (ELISA)

1 µg/mL

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 481-660 of human CACNB2 (NP_9638902)

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.64 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2806278

Product Specific Information

Immunogen sequence: ATSSLPLSPT LASNSQGSQG DQRTDRSAPI RSASQAEEEP SVEPVKKSQH RSSSSAPHHN HRSGTSRGLS RQETFDSETQ ESRDSAYVEP KEDYSHDHVD HYASHRDHNH RDETHGSSDH RHRESRHRSR DVDREQDHNE CNKQRSRHKS KDRYCEKDGE VISKKRNEAG EWNRDVYIRQ; Positive Samples: Mouse heart; Cellular Location: Cell membrane, Cytoplasmic side, Peripheral membrane protein, sarcolemma

Target Information

The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CAB1; CAB2; CACNLB1; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; CCHLB1; Lambert-Eaton myasthenic syndrome antigen B; MGC138502; MGC138504; MGC41896; myasthenic (Lambert-Eaton) syndrome antigen B; MYSB; Voltage-dependent L-type calcium channel subunit beta-2; voltage-gated calcium channel beta2 subunit transcript variant X13

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Gene Aliases: AW060387; CAB2; CACNB2; CACNLB2; CAVB2; Cavbeta2; Cchb2; MYSB

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UniProt ID: (Human) Q08289, (Mouse) Q8CC27, (Rat) Q8VGC3

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Entrez Gene ID: (Human) 783, (Mouse) 12296, (Rat) 116600

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Function(s)

voltage-gated calcium channel activity calcium channel regulator activity calcium channel activity protein binding high voltage-gated calcium channel activity protein kinase binding protein domain specific binding actin filament binding phosphoprotein binding voltage-gated calcium channel activity involved in cardiac muscle cell action potential voltage-gated calcium channel activity involved in AV node cell action potential voltage-gated ion channel activity

Process(es)

chemical synaptic transmission neuromuscular junction development visual perception positive regulation of calcium ion transport cardiac conduction calcium ion import calcium ion transmembrane transport membrane depolarization during AV node cell action potential regulation of heart rate by cardiac conduction establishment of protein localization to plasma membrane membrane depolarization during atrial cardiac muscle cell action potential regulation of voltage-gated calcium channel activity positive regulation of high voltage-gated calcium channel activity positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel transport ion transport calcium ion transport regulation of ion transmembrane transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CACNB2 Polyclonal Antibody

CACNB2 Antibody (PA5-90894) in IHC (P)

Product Details

PA5-90894

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

ELISA (ELISA)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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