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  • Primary Antibodies ›
  • CACNB2 Antibodies

Invitrogen

CACNB2 Polyclonal Antibody

Advanced Verification
View all (30) CACNB2 antibodies

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Datasheet
Protocols
Questions & Answers

Cite CACNB2 Polyclonal Antibody

  • Antibody Testing Data (4)
  • Advanced Verification (1)
CACNB2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CACNB2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CACNB2 Antibody (PA5-57230) in IHC (P)

Immunohistochemical analysis of CACNB2 in human prostate using CACNB2 Polyclonal Antibody (Product # PA5-57230) shows weak to moderate membranous positivity in smooth muscle cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CACNB2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CACNB2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CACNB2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CACNB2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CACNB2 Antibody
CACNB2 Polyclonal Antibody

Product Details

PA5-57230

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Calcium Channel 2. Recombinant protein control fragment (Product #RP-95805).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2639229

Product Specific Information

Immunogen sequence: RDSAYVEPKE DYSHDHVDHY ASHRDHNHRD ETHGSSDHRH RESRHRSRDV DREQDHNECN KQRSRHKSKD RYCEKDGEVI

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 78%.

Target Information

The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CAB1; CAB2; CACNLB1; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; CCHLB1; Lambert-Eaton myasthenic syndrome antigen B; MGC138502; MGC138504; MGC41896; myasthenic (Lambert-Eaton) syndrome antigen B; MYSB; Voltage-dependent L-type calcium channel subunit beta-2

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Gene Aliases: CACNB2; CACNLB2; CAVB2; MYSB

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UniProt ID: (Human) Q08289

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Entrez Gene ID: (Human) 783

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Function(s)
voltage-gated calcium channel activity calcium channel regulator activity calcium channel activity protein binding high voltage-gated calcium channel activity protein kinase binding protein domain specific binding actin filament binding phosphoprotein binding voltage-gated calcium channel activity involved in cardiac muscle cell action potential voltage-gated calcium channel activity involved in AV node cell action potential
Process(es)
chemical synaptic transmission neuromuscular junction development visual perception positive regulation of calcium ion transport cardiac conduction calcium ion import calcium ion transmembrane transport membrane depolarization during AV node cell action potential regulation of heart rate by cardiac conduction establishment of protein localization to plasma membrane membrane depolarization during atrial cardiac muscle cell action potential regulation of voltage-gated calcium channel activity positive regulation of high voltage-gated calcium channel activity positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
It has to be done as per old AB suggested Products section.
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