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  • Primary Antibodies ›
  • BMP-8 Antibodies

Fabgennix

BMP8 Polyclonal Antibody, Biotin

View all (6) BMP-8 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite BMP8 Polyclonal Antibody, Biotin

BMP8 Polyclonal Antibody, Biotin

Product Details

BMP8-BIOTIN

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 160-200 on human BMP8 protein
View immunogen

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: BMP; BMP-8; BMP-8A; BMP-8B; Bone morphogenetic protein; bone morphogenetic protein 8 (osteogenic protein 2); Bone morphogenetic protein 8A; Bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); MGC131757; OP-2; Osteogenic protein 2

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Gene Aliases: Bmp-8; Bmp7r1; BMP8; BMP8A; BMP8B; OP-2; OP2; Op3

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UniProt ID: (Human) Q7Z5Y6, (Human) P34820, (Mouse) P34821, (Mouse) P55105

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Entrez Gene ID: (Human) 353500, (Human) 656, (Mouse) 12163, (Rat) 680931, (Mouse) 12164, (Rat) 679119

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Function(s)
cytokine activity transforming growth factor beta receptor binding growth factor activity BMP receptor binding
Process(es)
ossification diet induced thermogenesis transforming growth factor beta receptor signaling pathway multicellular organism development germ cell development spermatogenesis positive regulation of pathway-restricted SMAD protein phosphorylation cell differentiation BMP signaling pathway growth regulation of apoptotic process regulation of MAPK cascade embryonic morphogenesis cartilage development SMAD protein signal transduction regulation of energy homeostasis cell development osteoblast differentiation negative regulation of insulin secretion skeletal system development
It has to be done as per old AB suggested Products section.
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