Invitrogen

BMP6 Recombinant Rabbit Monoclonal Antibody (6N5S9)

View all (19) BMP6 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
BMP6 Recombinant Rabbit Monoclonal Antibody (6N5S9)

Product Details

MA5-35530

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6N5S9

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 350-450 of human BMP6 (NP_0017091)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849430

Product Specific Information

Immunogen sequence: DGPYDKQPFM VAFFKVSEVH VRTTRSASSR RRQQSRNRST QSQDVARVSS ASDYNSSELK TACRKHELYV SFQDLGWQDW IIAPKGYAAN YCDGECSFPL N

Target Information

BMP6 is a member of bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, Bmp6 has a proposed role in early development. In addition, the fact that BMP6 is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: BMP; BMP 6; BMP-6; Bone morphogenetic protein; Bone morphogenetic protein 6; vegetal related growth factor (TGFB-related); vegetal-related (TGFB related) cytokine; VG-1-R; VG-1-related protein; Vg1-related sequence; VGR-1

View more View less

Gene Aliases: Bmp-6; BMP6; D13Wsu115e; VGR; VGR1

View more View less

UniProt ID: (Human) P22004, (Mouse) P20722, (Rat) Q04906

View more View less

Entrez Gene ID: (Human) 654, (Mouse) 12161, (Rat) 25644

View more View less

Function(s)
cytokine activity transforming growth factor beta receptor binding growth factor activity protein heterodimerization activity BMP receptor binding protein binding
Process(es)
ossification osteoblast differentiation eye development kidney development positive regulation of endothelial cell proliferation endochondral ossification type B pancreatic cell development cellular iron ion homeostasis immune response multicellular organism development positive regulation of pathway-restricted SMAD protein phosphorylation cell differentiation positive regulation of bone mineralization BMP signaling pathway male genitalia development positive regulation of chondrocyte differentiation positive regulation of aldosterone biosynthetic process growth regulation of apoptotic process regulation of MAPK cascade positive regulation of endothelial cell differentiation positive regulation of neuron differentiation positive regulation of osteoblast differentiation positive regulation of transcription from RNA polymerase II promoter cell development positive regulation of epithelial cell proliferation cartilage development SMAD protein signal transduction positive regulation of aldosterone secretion negative regulation of transcription from RNA polymerase II promoter skeletal system development inflammatory response response to activity positive regulation of lipopolysaccharide-mediated signaling pathway response to magnesium ion response to retinoic acid positive regulation of protein secretion response to glucocorticoid positive regulation of SMAD protein import into nucleus multicellular organismal iron ion homeostasis cellular response to mechanical stimulus cellular response to iron ion cellular response to BMP stimulus positive regulation of DNA-dependent DNA replication response to iron ion regulation of cell differentiation
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support