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  • Primary Antibodies ›
  • BLOC1S3 Antibodies

Bethyl Laboratories

BLOC1S3 Polyclonal Antibody

View all (5) BLOC1S3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite BLOC1S3 Polyclonal Antibody

  • Antibody Testing Data (2)
BLOC1S3 Antibody in Western Blot (WB)
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BLOC1S3 Antibody in Western Blot (WB)
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BLOC1S3 Antibody (A304-612A) in WB

Detection of human BLOC1S3 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-BLOC1S3 antibody (Product # A304-612A) (lot A304-612A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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BLOC1S3 Antibody in Western Blot (WB)
BLOC1S3 Antibody in Immunoprecipitation (IP)
BLOC1S3 Polyclonal Antibody

Product Details

A304-612A

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000-1:10,000
-

Immunoprecipitation (IP)

2-10 µg/mg lysate
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 1 to 50 of human Biogenesis of Lysosomal Organelles Complex-1, Subunit 3.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

phosphate/tris citrate, pH 7-8

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: biogenesis of lysosomal organelles complex-1, subunit 3; Biogenesis of lysosome-related organelles complex 1 subunit 3; biogenesis of lysosome-related organelles complex-1, subunit 3; BLOC-1 subunit 3; reduced pigmentation, mouse, homolog of

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Gene Aliases: BLOC1S3; BLOS3; HPS8; RP

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UniProt ID: (Human) Q6QNY0

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Entrez Gene ID: (Human) 388552

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Function(s)
molecular_function protein binding protein transmembrane transporter activity
Process(es)
eye development anterograde axonal transport platelet activation neuron projection development melanosome transport melanosome organization positive regulation of natural killer cell activation secretion of lysosomal enzymes endosome to melanosome transport response to drug pigmentation anterograde synaptic vesicle transport platelet dense granule organization protein transmembrane transport
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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