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Proteintech

BBS6 Polyclonal Antibody

View all (7) MKKS antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite BBS6 Polyclonal Antibody

  • Antibody Testing Data (5)
BBS6 Antibody in Immunocytochemistry (ICC/IF)
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BBS6 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 5

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BBS6 Antibody (13078-1-AP) in ICC/IF

IF result (cytoplasm and the base of cilia stain) of anti-BBS6 (13078-1-AP; 1:50) with hTERT-RPE1 cell (MeOH fixed) by Dr. Moshe Kim. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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BBS6 Antibody in Immunocytochemistry (ICC/IF)
BBS6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
BBS6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
BBS6 Antibody in Western Blot (WB)
BBS6 Antibody in Western Blot (WB)
BBS6 Polyclonal Antibody

Product Details

13078-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunocytochemistry (ICC/IF)

1:20-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

BBS6 Fusion Protein Ag3785 (223-570 aa encoded by BC028973)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SEVQLMRLL PIKKSTALKV ALFCTTLSGD TSDTGEGTVV VSYGVSLENA VLDQLLNLGR QLISDHVDLV LCQKVIHPSL KQFLNMHRII AIDRIGVTLM EPLTKMTGTQ PIGSLGSICP NSYGSVKDVC TAKFGSKHFF HLIPNEATIC SLLLCNRNDT AWDELKLTCQ TALHVLQLTL KEPWALLGGG CTETHLAAYI RHKTHNDPES ILKDDECTQT ELQLIAEAFC SALESVVGSL EHDGGEILTD MKYGHLWSVQ ADSPCVANWP DLLSQCGCGL YNSQEELNWS FLRSTCRPFV PQSCLPHEAV VSASNLTLDC LTAKLSGLQV AVETANLILD LSYVIEDKN (223-570 aa encoded by BC028973)

Target Information

Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Bardet-Biedl syndrome 6 protein; McKusick-Kaufman syndrome protein; McKusick-Kaufman syndrome protein; MKKS protein; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; Molecular chaperone MKKS; Protein Bbs6 homolog

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Gene Aliases: 1300013E18Rik; AI463362; AI957237; BBS6; HMCS; KMS; MKKS; MKS

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UniProt ID: (Human) Q9NPJ1, (Mouse) Q9JI70

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Entrez Gene ID: (Human) 8195, (Mouse) 59030, (Rat) 311456

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Function(s)
RNA polymerase II repressing transcription factor binding protein binding ATP binding unfolded protein binding nucleotide binding molecular_function
Process(es)
protein folding spermatid development sensory perception of smell negative regulation of gene expression artery smooth muscle contraction striatum development hippocampus development cerebral cortex development negative regulation of actin filament polymerization leptin-mediated signaling pathway negative regulation of GTPase activity nonmotile primary cilium assembly social behavior negative regulation of appetite by leptin-mediated signaling pathway positive regulation of multicellular organism growth vasodilation cilium assembly response to leptin photoreceptor cell maintenance negative regulation of blood pressure brain morphogenesis detection of mechanical stimulus involved in sensory perception of sound chaperone-mediated protein complex assembly cartilage development regulation of stress fiber assembly cilium morphogenesis regulation of cilium beat frequency involved in ciliary motility face development heart looping determination of left/right symmetry heart development visual perception gonad development melanosome transport fat cell differentiation intracellular transport pigment granule aggregation in cell center convergent extension involved in gastrulation biological_process
It has to be done as per old AB suggested Products section.
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