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Abnova
B4GAT1 Monoclonal Antibody (2H6)
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Product Details
H00011041-M03
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: AYVVPWQDPW EPFYVAGGKV PTFDERFRQY GFNRISQACE LHVAGFDFEV LNEGFLVHKG FKEALKFHPQ KEAENQHNKI LYRQFKQELK AKYPNSPRRC
Target Information
Beta-1,4-glucuronyltransferase involved in O- mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE, during synthesis of phosphorylated O- mannosyl glycan (PubMed:25279699, PubMed:25279697). Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:25279697). Required for axon guidance; via its function in O-mannosylation of alpha- dystroglycan (DAG1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: B3GNT1 (HGNC:15685); beta-1,3-N-acetylglucosaminyltransferase bGnT-6; Beta-1,4-glucuronyltransferase 1; EC 2.4.1.149; I-beta-1,3-N-acetylglucosaminyltransferase; iGnT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
Gene Aliases: B3GN-T1; B3GNT1; B3GNT6; B4GAT1; BETA3GNTI; iGAT; iGNT; MDDGA13
UniProt ID: (Human) O43505
Entrez Gene ID: (Human) 11041
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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