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  • Primary Antibodies ›
  • Aromatase Antibodies

Invitrogen

Aromatase Polyclonal Antibody

View all (22) Aromatase antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite Aromatase Polyclonal Antibody

  • Antibody Testing Data (1)
Aromatase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Aromatase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Aromatase Antibody (PA5-80534) in IHC (P)

Immunohistochemical staining of human Aromatase in human placenta with Aromatase Polyclonal Antibody (Product # PA5-80534, 1:1,000 dilution, formalin-fixed paraffin embedded sections). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Aromatase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

PA5-80534

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:2,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to the center region of the Human Aromatase/CYP19A1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS, pH 7

Contains

0.03% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2787838

Product Specific Information

This antibody has specificity for Human Aromatase/CYP19A1.

Target Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Aromatase; CYPXIX; Cytochrome P-450AROM; Cytochrome P450 19A1; cytochrome P450, family 19, subfamily A, polypeptide 1; cytochrome P450, subfamily XIX (aromatization of androgens); Estrogen synthase; estrogen synthetase; flavoprotein-linked monooxygenase; MGC104309; microsomal monooxygenase

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Gene Aliases: ARO; ARO1; CPV1; CYAR; CYP19; CYP19A1; CYPXIX; P-450AROM

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UniProt ID: (Human) P11511

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Entrez Gene ID: (Human) 1588

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Function(s)
iron ion binding steroid hydroxylase activity electron carrier activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen oxygen binding heme binding aromatase activity
Process(es)
negative regulation of chronic inflammatory response steroid biosynthetic process estrogen biosynthetic process androgen metabolic process negative regulation of macrophage chemotaxis sterol metabolic process oxidation-reduction process prostate gland growth
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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