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  • Primary Antibodies ›
  • Apolipoprotein H Antibodies

Invitrogen

Apolipoprotein H Polyclonal Antibody

View all (37) Apolipoprotein H antibodies

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Datasheet
Protocols
Questions & Answers

Cite Apolipoprotein H Polyclonal Antibody

  • Antibody Testing Data (2)
Apolipoprotein H Antibody in Immunocytochemistry (ICC/IF)
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Apolipoprotein H Antibody in Immunocytochemistry (ICC/IF)
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Apolipoprotein H Antibody (PA5-114866) in ICC/IF

Immunocytochemistry analysis of Apolipoprotein H in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114866) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Apolipoprotein H Antibody in Immunocytochemistry (ICC/IF)
Apolipoprotein H Antibody in Western Blot (WB)
Apolipoprotein H Polyclonal Antibody

Product Details

PA5-114866

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

Affinity Purification (AP)

-
- -
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human APOH(Accession P02749), corresponding to amino acid residues K306-C345.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2899502

Product Specific Information

Antibody detects endogenous levels of total APOH.

Target Information

Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 2GPI; Activated protein C-binding protein; Anticardiolipin cofactor; APC inhibitor; Apo-H; Apolipoprotein H; apolipoprotein H (beta-2-glycoprotein I); B2GPI; beta(2)GPI; Beta-2-glycoprotein 1; Beta-2-glycoprotein I

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Gene Aliases: APOH; B2G1; B2GP1; B2GPI; beta-2-GPI; beta2-GPI; BG

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UniProt ID: (Human) P02749, (Mouse) Q01339

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Entrez Gene ID: (Human) 350, (Rat) 287774, (Mouse) 11818

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Function(s)
glycoprotein binding protein binding phospholipid binding heparin binding lipid binding identical protein binding lipoprotein lipase activator activity
Process(es)
negative regulation of endothelial cell proliferation triglyceride metabolic process blood coagulation blood coagulation, intrinsic pathway negative regulation of endothelial cell migration negative regulation of angiogenesis regulation of blood coagulation negative regulation of blood coagulation organ regeneration plasminogen activation negative regulation of myeloid cell apoptotic process triglyceride transport negative regulation of smooth muscle cell apoptotic process positive regulation of lipoprotein lipase activity regulation of fibrinolysis negative regulation of fibrinolysis platelet degranulation aging positive regulation of triglyceride catabolic process positive regulation of blood coagulation response to triglyceride negative regulation of respiratory burst
It has to be done as per old AB suggested Products section.
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