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Invitrogen
Annexin A6 Monoclonal Antibody (4G3)
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FIGURE: 1 / 2
Annexin A6 Antibody (MA5-47434) in ICC/IF
Product Details
MA5-47434
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
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Target Information
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: 67 kDa calelectrin; Annexin A6; Annexin VI; annexin VI (p68); annexin VI, p68; Annexin-6; calcium-binding protein 65/67; calcium-binding protein CATA 65/67; calcium-binding protein p68; calelectrin; calphobindin II; Calphobindin-II; CBP 65/67; Chromobindin-20; CPB-II; Lipocortin VI; p68; p70; Protein III; testis secretory sperm-binding protein Li 198a
Gene Aliases: ANX6; ANXA6; AnxVI; AW107198; Cabm; Camb; CBP68; CPB-II
UniProt ID: (Human) P08133, (Mouse) P14824
Entrez Gene ID: (Human) 309, (Dog) 479325, (Mouse) 11749, (Rat) 79125
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