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Invitrogen
Angiogenin Monoclonal Antibody (14017.7)
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Product Details
MA1-20177
Species Reactivity
Published species
Host/Isotype
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Immunogen
Conjugate
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Product Specific Information
Recommended positive controls: mouse liver.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Angiogenin; angiogenin, ribonuclease, RNase A family, 5; epididymis luminal protein 168; MGC22466; MGC71966; Ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5
Gene Aliases: ALS9; ANG; HEL168; RAA1; RNASE4; RNASE5
UniProt ID: (Human) P03950
Entrez Gene ID: (Human) 283
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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