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  • Primary Antibodies ›
  • Acetylcholinesterase Antibodies

Invitrogen

Acetylcholinesterase Polyclonal Antibody

View all (20) Acetylcholinesterase antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Acetylcholinesterase Polyclonal Antibody

  • Antibody Testing Data (4)
Acetylcholinesterase Antibody in Immunocytochemistry (ICC/IF)
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Acetylcholinesterase Antibody in Immunocytochemistry (ICC/IF)
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Acetylcholinesterase Antibody (PA5-15010) in ICC/IF

Immunocytochemistry analysis of Acetylcholinesterase in NCI-H460 cells. Samples were incubated in Acetylcholinesterase polyclonal antibody (Product # PA5-15010) followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Acetylcholinesterase Antibody in Immunocytochemistry (ICC/IF)
Acetylcholinesterase Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Acetylcholinesterase Antibody in Western Blot (WB)
Acetylcholinesterase Antibody in Flow Cytometry (Flow)
Acetylcholinesterase Polyclonal Antibody

Product Details

PA5-15010

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:10-1:50
-

Immunocytochemistry (ICC/IF)

1:10-1:50
-

Flow Cytometry (Flow)

1:10-1:50
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human ACHE
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2223329

Target Information

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Acetylcholinesterase; acetylcholinesterase (Yt blood group); AChE; apoptosis-related acetylcholinesterase; EC 3.1.1.7; OTTHUMP00000211349; OTTHUMP00000211356; Yt blood group

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Gene Aliases: ACEE; ACHE; ARACHE; N-ACHE; YT

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UniProt ID: (Human) P22303

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Entrez Gene ID: (Human) 43

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Function(s)
beta-amyloid binding acetylcholinesterase activity cholinesterase activity protein binding collagen binding hydrolase activity serine hydrolase activity acetylcholine binding protein homodimerization activity laminin binding protein self-association
Process(es)
acetylcholine catabolic process in synaptic cleft regulation of receptor recycling osteoblast development DNA replication acetylcholine catabolic process phosphatidylcholine biosynthetic process cell adhesion nervous system development synapse assembly muscle organ development cell proliferation response to wounding receptor internalization negative regulation of synaptic transmission, cholinergic neurotransmitter biosynthetic process amyloid precursor protein metabolic process neurotransmitter receptor biosynthetic process positive regulation of protein secretion protein tetramerization retina development in camera-type eye
It has to be done as per old AB suggested Products section.
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